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Occupational Ototoxins (Ear Poisons) and Hearing Loss

    https://phc.amedd.army.mil/PHC%20Resource%20Library/Ototoxin_FS_51-002-0713.pdf#:~:text=Since%20the%20exposure%20threshold%20for%20such%20ototoxic%20effects,ensure%20the%20collection%20of%20data%20from%20sub-OEL%20exposures.
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Looking beyond the audiogram in ototoxicity associated ...

    https://pubmed.ncbi.nlm.nih.gov/31865419/
    Introduction: Ototoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors. Discussion: In this article, we highlight important aspects of the evaluation of ototoxicity with the aim to increase awareness of Oncologists in this regard. Standard pure tone audiometry alone is inadequate for this context.

Audiological Monitoring of Patients Receiving Ototoxic Drugs

    https://www.ncrar.research.va.gov/Education/Documents/Ototoxicity_Documents_A/Audiological_Monitoring_of_Patients.pdf
    est detection of ototoxic damage. Ototoxicity identifi-cation before speech frequencies are compromised can alert providers prior to impairment of communication ability. The foundation of ototoxicity monitoring is the serial collection of pure-tone behavioral thresholds. Ultra-high frequency audiometry and evoked

Cisplatin ototoxicity: the importance of baseline audiometry

    https://pubmed.ncbi.nlm.nih.gov/10362343/
    Audiograms were obtained from 217 patients before treatment with cisplatin-based chemotherapy for cancers of the esophagus, lung, or head and neck. Posttreatment audiometry then was conducted in … The role and optimal use of audiometry in monitoring for cisplatin ototoxicity are incompletely defined.

Clinical Trials, Ototoxicity Grading Scales,and the ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260812/
    Baseline audiogram representing air conduction hearing thresholds from one ear of an adolescent female prior to exposure to a potential ototoxic medication. Both the SIOP and Brock scales do not account for pre-existing hearing loss; this audiogram would be graded a 3 on both scales prior to any ototoxic exposure.

Ototoxicity—The Hidden Menace. Part II: Ototoxicity and ...

    https://hearinglosshelp.com/blog/ototoxicity-the-hidden-menace-part-ii-ototoxicity-and-the-practice-of-audiology/
    High-frequency audiometry can reveal the early effects of ototoxic drugs before tinnitus appears or hearing damage is visible on a conventional audiogram (250 and 8,000 Hz).

Ototoxicity: A Challenge in Diagnosis and Treatment

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894487/
    Epidemiology. Ototoxicity occurs in all age groups. Although it is well documented, the global magnitude of its incidence is unknown due to various reasons such as existence of varied and diverse criteria to define ototoxicity [Chang grading system, Tune grading system, American Speech-Language-Hearing Association (ASHA) criteria etc.], wide range of reactions …

American Academy of Audiology Position Statement and ...

    https://www.audiology.org/wp-content/uploads/2021/05/OtoMonGuidelines.pdf_539974c40999c1.58842217.pdf
    ototoxic medications, which emphasizes another reason to obtain pre -treatment audiometry/audiologic data whenever possible. This also underscores the importance of the clinician’s mos t fundamental tool--a thorough history. It should not be assumed, additionally, that ototoxic exposure is limit ed to heath care. It is well known, for example ...

Ototoxicity - Washington University in St. Louis

    http://hearing.wustl.edu/Hearing-Education-Center/Disease-Diagnosis-Treatment/Ototoxicity
    The exact mechanisim is not fully understood but certain drugs can destroy or damage parts of the inner ear (cochlea) or hearing nerve. Some types of medications may be more ototoxic than others. It is also dependent on the dosage and the duration of time that the medication is used. Some medications may cause more damage to the hearing systems ...

Audiological monitoring in ototoxicity - Are we doing ...

    https://www.entandaudiologynews.com/features/audiology-features/post/audiological-monitoring-in-ototoxicity-are-we-doing-enough
    In this article Ghada Al-Malky explores the dichotomy of life-saving, yet hearing loss-causing medication, and questions whether the hearing healthcare community is doing enough to prevent preventable hearing loss.. Ototoxicity is the damage to hearing and / or balance functions of the ear due to exposure to drugs or chemicals. There are over 200 prescription …

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