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Nitrofurantoin - StatPearls - NCBI Bookshelf

    https://www.ncbi.nlm.nih.gov/books/NBK470526/
    Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infection. It is effective against most gram-positive and gram-negative organisms. Nitrofurantoin was approved by the FDA in 1953 for treatment of lower urinary tract infection.

Nitrofurantoin: MedlinePlus Drug Information

    https://medlineplus.gov/druginfo/meds/a682291.html
    Nitrofurantoin comes as a capsule and a liquid to take by mouth. Nitrofurantoin usually is taken two or four times a day for at least 7 days. Take it with a full glass of water and with meals. Try to take nitrofurantoin at the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to ...

Nitrofurantoin - PubMed

    https://pubmed.ncbi.nlm.nih.gov/29262089/
    Nitrofurantoin is an antibiotic medication that is used for the treatment of uncomplicated lower urinary tract infection. It is effective against most gram-positive and gram-negative organisms. Several major guidelines have declared nitrofurantoin as the first-line therapy for the treatment of uncomplicated lower urinary tract infections.

Nitrofurantoin: mechanism of action and implications for ...

    https://pubmed.ncbi.nlm.nih.gov/7928834/
    Nitrofurantoin is an effective urinary tract antibacterial to which no clinically significant resistance development has occurred. We have previously shown that nitrofurantoin susceptibility in bacteria correlates with the presence of bacterial nitroreductases which convert nitrofurantoin to highly reactive electrophilic intermediates.

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