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List of Ototoxic Medications - Sound Relief Hearing Center

    https://www.soundrelief.com/list-of-ototoxic-medications/
    List of Ototoxic Medications. There are more than 450 prescription and over-the-counter drugs that can trigger tinnitus, make existing tinnitus worse, or cause a new tinnitus sound to appear. In fact, most drug classes have tinnitus-causing drugs sprinkled throughout. For example, antibiotics, painkillers, anti-anxiety, and anti-depression drugs, antimalarial …

Drug-Induced Ototoxicity - Ear, Nose, and Throat …

    https://www.merckmanuals.com/professional/ear,-nose,-and-throat-disorders/inner-ear-disorders/drug-induced-ototoxicity
    Streptomycin tends to cause more damage to the vestibular portion than to the auditory portion of the inner ear. Although vertigo and difficulty maintaining balance tend to be temporary, severe loss of vestibular sensitivity may persist, sometimes permanently. Loss of vestibular sensitivity causes difficulty walking, especially in the dark, and oscillopsia (a sensation of bouncing of the …

Audiological Monitoring of Patients Receiving Ototoxic Drugs

    https://www.ncrar.research.va.gov/Education/Documents/Ototoxicity_Documents_A/Audiological_Monitoring_of_Patients.pdf
    ototoxic drugs (Hodges & Lonsbury-Martin, 1998). Evoked OAEs are acoustic responses generated by outer hair cells within the cochlear end organ, suggesting that OAEs may be a sensitive indicator of ototoxic dam-age. Distortion product OAEs (DPOAEs), responses elicited using two tones, are particularly effective for the early detection of ototoxicity.

Nonclinical Assessment of Otic & Vestibular Toxicity: …

    https://www.fda.gov/downloads/Drugs/NewsEvents/UCM621085.pdf
    the speaker and should not be ... Testing Local Toxicity of Human Otic Drugs. 7 ... assessments may detect otic or vestibular toxicity but sensitivity

Cognitive toxicity of drugs used in the elderly

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181655/
    Many of the commonly used medications, such as digoxin, psychotropics, and those with anticholinergic (muscarinic-blocking) properties, have been well documented as causes of cognitive disturbances, even when used alone. 13,14,22-24 A number of intrinsic physiologic alterations also put older individuals at increased risk for cognitive toxicity, …

Predictive value of the lymphocyte toxicity assay in the ...

    https://pubmed.ncbi.nlm.nih.gov/21053997/
    Background: Drug hypersensitivity syndrome (DHS) is a rare but potentially fatal adverse drug reaction that develops in susceptible patients following exposure to certain drugs. Because of the variable clinical picture of DHS and its resemblance to other diseases, the diagnosis of DHS is challenging. The lymphocyte toxicity assay (LTA) is an in vitro test that has been used in the …

Medications and other Agents that Increase Sensitivity to ...

    https://www.dhs.wisconsin.gov/radiation/medications.htm
    Many medications and supplements contain ingredients that may cause photosensitivity, which is defined as a chemically induced change in the skin that makes an individual unusually sensitive to light. An individual who has been photosensitized may develop a rash, sunburn, or other adverse effect from exposure to light of an intensity or duration that …

Ototoxicity - VeDA

    https://vestibular.org/article/diagnosis-treatment/types-of-vestibular-disorders/ototoxicity/
    Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain). Because the inner ear is involved in both hearing and balance, ototoxicity can result in disturbances of either or …

Managing and Monitoring Side Effects and Toxicities of ...

    https://www.ndhealth.gov/hiv/Docs/LunchnLearns/2018/09_AntiTBAdverseDrugEffects.pdf
    Adverse Drug Reaction Assessment: Ask all the b elow questi ons to monitor for medication toxicity , noting that some symptoms may be more commonly associated with certain medications. Those with** are associated with second -line drugs ; those with are associated with Isoniazid/Rifapentine (3HP) but may also be pres ent in

Toxic Drugs: When Medicine Makes You Sick - AARP The …

    https://www.aarp.org/health/drugs-supplements/info-08-2010/toxic-drugs-when-medicine-makes-you-sick.html
    Drug toxicity is "a major public-health issue even for people in their 40s and 50s," says Mukaila A. Raji, M.D., chief of geriatric medicine at the University of Texas Medical Branch in Galveston. "Most drugs are eliminated from the body through the kidneys and liver, but starting around the fourth decade we start accumulating fat and lose ...

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