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Baseline audiological profiling of South African females ...
https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-021-01313-5#:~:text=Cisplatin%20treatment%20is%20associated%20with%20ototoxicity%2C%20often%20resulting,in%20order%20to%20evaluate%20the%20extent%20of%20cisplatin-associated-ototoxicity.
Cisplatin ototoxicity: the importance of baseline audiometry
https://pubmed.ncbi.nlm.nih.gov/10362343/
The role and optimal use of audiometry in monitoring for cisplatin ototoxicity are incompletely defined. Audiograms were obtained from 217 patients before treatment with cisplatin-based chemotherapy for cancers of the esophagus, lung, or head and neck. Posttreatment audiometry then was conducted in 53 of these patients.
Cisplatin Ototoxicity: The Importance of Baseline ...
https://journals.lww.com/amjclinicaloncology/Abstract/1999/06000/Cisplatin_Ototoxicity__The_Importance_of_Baseline.20.aspx
The role and optimal use of audiometry in monitoring for cisplatin ototoxicity are incompletely defined. Audiograms were obtained from 217 patients before treatment with cisplatin-based chemotherapy for cancers of the esophagus, lung, or head and neck. Posttreatment audiometry then was conducted in 53 of these patients.
Ototoxicity in patients receiving cisplatin: importance of ...
https://pubmed.ncbi.nlm.nih.gov/7198012/
Ototoxicity resulted in dose modification or cessation of treatment in only three patients, and in each case the decision to modify the dose was made on the basis of symptoms of ototoxicity rather than on the audiometric findings. We conclude that audiometry has a limited role in the routine management of patients receiving cisplatin treatment.
Cisplatin-Induced Ototoxicity: Effects, Mechanisms and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606684/
While all evidence indicates that cisplatin ototoxicity is dose-dependent and progressive, the largest prospective study evaluating audiometric data from patients treated with cisplatin showed a tendency of hearing loss to reach a plateau, with a clear predominance of the lesion in the higher frequencies: for frequencies above 8 kHz the average hearing loss stood at …
The Role of Audiometry prior to High-Dose Cisplatin in ...
https://pubmed.ncbi.nlm.nih.gov/28511189/
Objectives: To analyze the role of audiometry in considering change to a less ototoxic treatment in head and neck cancer (HNC) patients. Methods: Consecutive patients prescribed high-dose cisplatin (100 mg/m2) between January 2013 and February 2015 were enrolled. Audiometry was performed at baseline and before cisplatin. Change to a less ototoxic agent or reduced …
Cisplatin-Associated Ototoxicity: A Review for the Health ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223030/
This review provides an up-to-date overview of cisplatin-associated ototoxicity, namely, its clinical features, incidence rates, and molecular and cellular mechanisms and risk factors, to health care practitioners managing the patient with cancer, and highlights the need for a team-based approach to complement an audiological monitoring programme to mitigate any …
Pharmacology and Ototoxicity: A Review of Cisplatin ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486385/
This review has highlighted that cisplatin ototoxicity is a common side effect of cisplatin chemotherapy that may negatively affect the quality of life of patients with cancer. The different molecular and cellular mechanisms involved in cisplatin-associated ototoxicity highlight the complexity of this condition and the consequent difficulty in identifying an effective …
Clinical implications - Ototoxicity in patients receiving ...
https://1library.net/article/clinical-implications-ototoxicity-patients-receiving-concurrent-cisplatin-cranial.zx8xjkvq
In document Ototoxicity in patients receiving concurrent cisplatin and cranial irradiation therapy for the treatment of head and neck cancers: an audiometric follow-up (Page 95-99) Based on the results of the present study, there are two main clinical implications that are discussed below: participant‘s eligibility to receive funding for ...
Aims of the current study - Ototoxicity in patients ...
https://1library.net/article/aims-current-ototoxicity-patients-receiving-concurrent-cisplatin-cranial.zx8xjkvq
The first aim is to investigate the prevalence of ototoxicity in head and neck oncology patients who received cisplatin in combination with cranial irradiation. Guidelines established by ASHA emphasise the importance of pre-treatment assessment to provide a baseline measure for each individual patient.
Ototoxicity: A Challenge in Diagnosis and Treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894487/
The cisplatin ototoxicity occurs between 23% and 50% in adults and up to 60% in children [4,6]. However, some studies have reported elevated hearing thresholds in up to 100% of cisplatin-treated cancer patients [7,8], while it is estimated to be 63% with aminoglycosides and 6-7% with furosemide . In addition, incidence severity of ototoxic hearing loss seems to be dose …
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